Venezuela has a rich cultural heritage. From the original American Indians to the Spanish and Africans who arrived after the Spanish conquest, the 17th century waves of immigration brought many Italians, Portuguese, Arabs, browns, Germans, Moroccan Jews, and others from the bordering countries of South America. About 93% of Venezuelans live in urban areas in the northern part of the country. Even though almost half of the land area is south of the Orinoco River, only 5% of the population live in that area.

Venezuela's heritage, art, and culture have been heavily influenced by the Caribbean context. These elements extend to its historic buildings, architecture, art, landscape, boundaries, and monuments. Venezuelan culture has been shaped by Indigenous, Spanish and African influences. Before this period, indigenous culture was expressed in art (petroglyphs), crafts, architecture (shabonos), and social organization. Aboriginal culture was subsequently assimilated by Spaniards; over the years, the hybrid culture had diversified by region.

Venezuela, like most South American nations, is a predominantly Catholic nation. The influence of the Catholic Church was introduced in its colonization by Spain. According to government estimates, 92 percent of the population is at least nominally Roman Catholic, and the remaining 8 percent protestant, a member of another religion, or atheist. The Venezuelan Evangelical Council estimates that Evangelical Protestants constitute 10 percent of the population.

The Muslim community of more than 100,000 is concentrated among persons of Lebanese and Syrian descent living in Nueva Esparta State, Punto Fijo and the Caracas area. The Jewish community numbers approximately 13,000 and is mainly concentrated in Caracas.

Currently there are approximately 153,000 Mormons (LDS church) mostly in and around Caracas.

Venezuela is also notable for its significant syncretic religious traditions, most notably those revolving around the figures of Maria Lionza and Jose Gregorio Hernandez.

In Venezuela, a growing population Santeria followers has been growing since 2008. The rituals can cost 40,000 bolivars and include the slaughtering of a rooster, a chicken, or a goat.